Cyclobenzaprine should be avoided in patients with which condition?

Cyclobenzaprine should be avoided in patients with which condition?

• A. Angle-closure glaucoma
• B. Migraine
• C. Hyperlipidemia
• D. Celiac disease

Answer: (A)

The key concept is that cyclobenzaprine has anticholinergic effects that can dilate the pupil and reduce drainage in the eye. In angle-closure glaucoma, this dilation can push the iris against the drainage angle, sharply increasing intraocular pressure. That makes angle-closure glaucoma a contraindication for cyclobenzaprine. Other conditions listed—migraine, hyperlipidemia, celiac disease—do not create the same acute risk with this medication, so they aren’t the primary reason to avoid it.

The key concept is that cyclobenzaprine has anticholinergic effects that can dilate the pupil and reduce drainage in the eye. In angle-closure glaucoma, this dilation can push the iris against the drainage angle, sharply increasing intraocular pressure. That makes angle-closure glaucoma a contraindication for cyclobenzaprine. Other conditions listed—migraine, hyperlipidemia, celiac disease—do not create the same acute risk with this medication, so they aren’t the primary reason to avoid it.